GLUTES® (Capsules)
 


For Healthy & Strong spine

Modern lifestyle with little exercise, bad posture and long working hours, have contributed to the prevalence of spondylitis. There are two kinds of spondylitis and they are Cervical and Ankylosing.

Cervical spondylitis is a type of arthritis affecting the intervertebral discs of the cervical spine, producing pain in the neck region. This problem causes pain, stiffness and numbness in the neck - often running down the arms. The main causative factor is the aging of bones and joints. Trauma, incorrect posture of body, prolonged typing or writing with flexion of neck aggravates the symptoms.

Ankylosing spondylitis (AS) is a rheumatic disease that causes arthritis of the spine and sacroiliac joints and can be associated with inflammation of the eyes, lungs, and heart valves. It varies from intermittent episodes of back pain that occur throughout life to a severe chronic disease that attacks the spine, peripheral joints and other body organs, resulting in severe joint and back stiffness, loss of motion and deformity as life progresses.

Our product GLUTES® is a unique blend of Glucosamine, Amla, Ginger and Curcumin. Glucosamine which supports healthy joint functions and helps rebuild the damaged cartilage; Amla fruit (Emblica officinalis Linn) which contributes to healthy bones due to its anti – inflammatory and antioxidant property; potentiated by Ginger (Zingiber officinalis Linn), an herbal bioenhancer. Apart from this bioenhancing property, Ginger possesses anti – inflammatory and analgesic activities and Curcumin (Extracted from Curcuma longa Linn) an active ingredient of spice turmeric is known for its anti-inflammatory properties.

GLUTES® is generally safe to the patients of spondylitis and does not cause stomach problems as those of painkillers / NSAIDs. Further, NSAIDs do not act on the disease process but merely mask the symptoms where as GLUTES® not only relieve pain & swelling but also helps reversing the disease process.

 

 

 

 

 

 

 
 
Ingredients Each Hard Gelatine Capsule Contains:
Glucosamine sulphate                            250 mg
Extract of Amla (Embilica officinalis)          50 mg
Extract of Ginger (Zingiber officinalis)         50 mg
Curcumin (extracted from Curcuma longa) 10 mg
Application Anti Spondylitic Dietary supplement*
Serving size One Capsule
Safety This health supplement is considered safe when used in accordance with proper dosing guidelines as indicated
Caution In general, the adverse effects that were reported were mild and most often related to gastrointestinal complaints. Keep out of reach of children, discontinue if unusual symptoms occur, do not use in pregnant and lactating women. Consult your doctor if adverse effects persist
Packing 60 capsules in one HDPE Container
*Disclaimer These statements have not been evaluated by the US Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease

References :

Glucosamine sulphate

  1. Dietary Supplements: A Framework for Evaluating Safety (IOM/NRC, 2004).

  2. Update on Glucosamine for Osteoarthritis (2001). Medical Letter 43; 111-112.

  3. Long-term effects of Glucosamine sulphate on Osteoarthritis progression: a randomized, placebo - controlled clinical trial. Reginster et al (2001): The Lancet 357: 251-256.

  4. Glucosamine and Chondroitin for treatment of OA; A systemic Quality assessment and Meta analysis. J McAlindon TE and others (2000): AMA 283; 1469-1475.

  5. Hyaluronan, Glucosamine & Chondroitin sulfate, roles for therapy in arthritis. Constatz RB (1988): Text book of Rhuematology, W B Saunders - Philladelphia.

  6. Double blind clinical evaluation of the relative efficacy of Ibuprofen and Glucosaminesulphate in the Management of Osteoarthritis of the Knee in out patients. Vazal et al (1982) : Curr Med Res Opin 8; 145-9.

  7. Therapeutic activity of oral Glucosamine Sulphate in Osteoarthrosis; a placebo controlled double blind investigation. Drovanti A et al (1980): Clin Ther 3; 260 – 72.

    Curcuma longa

  8. Safety and anti-inflammatory activity of Curcumin: a component of turmeric (Curcuma longa) (2003): Chainani - Wu N. J Alternate Complement Med 9, 161 - 168.

  9. Anti-inflammatory activity of Curcumin analogues. G Rao T Set al (1982): Indian J Medical Res 75; 574 - 578.

  10. Preliminary studies on anti-rheumatic activity of Curcumin. Deodhar S D et al (1980): Indian J Med Res 71; 632-634.

  11. Pharmacology of Diferuloyl methane (Curcumin), a non - steroidal anti-inflammatory agent. Srimal R C & Dhawan B N (1973): J Pharmacol 25; 447-452.

    Zingiber officinale

  12. Effects of Ginger (Zingiber officinale Rosc) on decreasing the production of inflammatory mediators in sow Osteoarthrotic cartilage explants. Shen C.L, Hong K.J, Kim S.W. J Med Food. 2003 winter; 6(4): 323-8

  13. Bioavailability enhancing activity of Zingiber officinale Linn and its extracts/fractions there of. Patent number: WO03049753, Publication date: 2003-06-19, Application number:WO2002IB05309 20021212, PATENT COOPERATION TREATY APPLICATION, JUN 2003.

  14. Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorders; Srivastava KC, Mustafa T. Medical Hypothesis, 39 (4), Dec 1992: 342 - 348.

  15. Ginger (Zingiber officinale) and Rheumatic disorders: Srivastava KC, Mustafa T. Med Hypothesis. 1989 May; 29(1): 25-8

    Emblica officinalis

  16. Anti oxidant activity of active tannoid principles of Embilica officinalis (Amla). Bhattacharya A et al. Indian J Exp Biol. 1999 Jul; 37(7):676- 80.

  17. Antioxidant activity of tannoid principles of Emblica officinalis (Amla) in chronic stress induced changes in rat brain. Bhattacharya A et al. Indian J Exp Biol. 2000 Sep; 38(9):877-80.

  18. Anti- inflammatory activity of extracts from leaves of Phyllanthus emblica. Ihantola-Vormisto A et al, Planta Med. 1997 Dec;63(6):518-24.

  19. Anti- inflammatory activities of Emblica officinalis Gaertn leaf extracts. Asmawi MZ et al, J Pharm Pharmacol. 1993 Jun;45(6):581-4.

  20. Immunomodulatory effects of agents of plant origin. Ganju L et al, Biomed Pharmacother. 2003 . Sep;57(7):296-300.

  21. Anti-inflammatory activities of Aller-7, a novel polyherbal formulation for allergic rhinitis. Pratibha N et al, Int J Tissue React. 2004;26(1-2):43-51.

  22. Medicinal plants from Nepal; II. Evaluation as inhibitors of lipid peroxidation in biological membranes. Kumar KC S, Muller K. J Ethnopharmacol. 1999 Feb;64(2):135-9.

  23. Identification of pyrogallol as an antiproliferative compound present in extracts from the medicinal plant Emblica officinalis: effects on in vitro cell growth of human tumor cell lines. Khan MT et al, Int J Oncol.02 Jul;21 (1):187-92.

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